Herb-Drug Interaction between Echinacea purpurea and Etravirine in HIV-Infected Patients
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چکیده
منابع مشابه
Herb-drug interaction between Echinacea purpurea and etravirine in HIV-infected patients.
The aim of this open-label, fixed-sequence study was to investigate the potential of the botanical supplement Echinacea purpurea to interact with etravirine, a nonnucleoside reverse transcriptase inhibitor of HIV. Fifteen HIV-infected patients receiving antiretroviral therapy with etravirine (400 mg once daily) for at least 4 weeks were included. E. purpurea root/extract-containing capsules wer...
متن کاملHerb-drug interaction between Echinacea purpurea and darunavir/ritonavir in HIV-infected patients
The aim of this open-label, fixed-sequence study was to investigate the potential of Echinacea purpurea, a commonly used botanical supplement, to interact with the boosted protease inhibitor darunavir-ritonavir. Fifteen HIV-infected patients receiving antiretroviral therapy including darunavir-ritonavir (600/100 mg twice daily) for at least 4 weeks were included. E. purpurea root extract capsul...
متن کاملEtravirine concentrations in seminal plasma in HIV-infected patients.
OBJECTIVES To determine etravirine concentrations and the HIV-1 viral load (VL) in blood plasma (BP) and seminal plasma (SP) of HIV-infected patients. METHODS Ten adult antiretroviral-experienced HIV-1 patients receiving an etravirine-containing regimen for at least 1 month were enrolled. Semen and blood samples were collected ~12 or 24 h after the last etravirine dose, depending on twice-dai...
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BACKGROUND The study goal was to describe etravirine pharmacokinetics during pregnancy and postpartum in HIV-infected women. METHODS IMPAACT P1026s and PANNA are on-going, non-randomized, open-label, parallel-group, multi-center phase-IV prospective studies in HIV-infected pregnant women. Intensive steady-state 12-h pharmacokinetic profiles were performed from 2nd trimester through postpartum...
متن کاملHigh-potency Anti-influenza Therapy by a Combination of Echinacea purpurea fresh herb and root tinctures
Article history: Received on: 26/10/2013 Revised on: 27/11/2013 Accepted on: 14/12/2013 Available online: 30/12/2013 The medicinal plant Echinacea purpurea (EP) contains potent antiviral and anti-inflammatory activities, which are believed to be responsible for the efficacy of such preparations in the treatment of colds and ‘flu. To determine to what extent the processes of drying, composition ...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2012
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.01205-12